The enclosed dataset comprises near-infrared (NIR) spectra of fingernails taken from healthy (class 1) and breast cancer individuals (class 2) measured using the Viavi MicroNIR spectrometer (Viavi Solutions Inc., USA), that weights around 50 g and has dimensions of 45 by 42 mm (Figure 1). Participants diagnosed with breast cancer were of stages I (n = 1), III (n = 3) and IV (n = 2). Spectra were measured over the wavelength range of 980 – 1670 nm with resolution of 6.25 nm per pixel.

The enclosed dataset comprises Raman spectra of fingernails taken from healthy, unhealthy, cardiovascular, diabetic and cardiovascular-diabetic participants measured using the portable Agilent Resolve Raman spectrometer equipped with an 830 nm laser wavelength (Agilent Resolve Raman Spectrometer).

The enclosed dataset comprises near-infrared (NIR) spectra of human fingernails taken from healthy, unhealthy, cardiovascular, diabetic, cardiovascular-diabetic fingernails measured using the Perkin Elmer Spectrum Two N Fourier Transform (FT)-NIR spectrometer equipped with a NIR module (NIRM) (Perkin Elmer Spectrum Two N FT-NIR spectrometer) . Cardiovascular diseases (CVDs) included atrial fibrillation, heart disease (unspecified) and hypertension.

The enclosed dataset comprises attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectra of human fingernails taken from healthy, unhealthy, cardiovascular, diabetic and cardiovascular-diabetic fingernails measured using the portable Agilent 4500a attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectrometer equipped with an ATR diamond (Agilent 4500 Series Portable FTIR Spectrometer).